Immediate Vascular Photochemical Reactions to Infrared Laser Irradiation in Normal Volunteers

Background: There are evidences that low level laser therapy (LLLT) stimulates wound healing. Objective: The study aimed at investigating the exact vascular mechanisms through which infrared (IR) laser acts to promote wound healing. Participants: Thirty normal female volunteers were selected from the female section, Faculty of Applied Medical Sciences, King Abdul-Aziz University. They were randomly divided into three equal study groups (G1, G2, and G3). Methods: Five ml. of whole blood were collected in a plane tube from all volunteers for the analysis of lipid profile including cholesterol (Chol); triglyceride (TGL); low density lipoprotein (LDL) and high density lipoprotein (HDL). Other five ml of blood were collected for the performance of glycated hemoglobin (HbA1c), hemoglobin (Hgb) and red blood cells (RBCs) count before and immediately after receiving continuous IR laser (810 nm, 100 mW). The irradiation doses were 12 J/cm for 120 sec, 6 J/cm for 60 sec and 1.4 J/cm for 14 sec in groups one, two, and three respectively. Results: There was a significant increase in Chol, TGL, HbA1c%, Hgb concentration and RBCs count after irradiation. On the other hand, there was no significant difference in LDL or HDL concentration in the three groups. Conclusion: Infrared laser was effective in increasing the levels of different blood components that are important for wound healing processes with the best results obtained from laser dosage of 12 J/cm. [Mohammed H Saiem Al-Dahr and Enas Elsayed. Immediate Vascular Photochemical Reactions to Infrared Laser Irradiation in Normal Volunteers. Journal of American Science 2011;7(6):203-208]. (ISSN: 1545-1003). http://www.americanscience.org.